Speakers

Chairman

Zhongze Gu
Professor, Cheung Kong Scholars, Fellow of the American Academy of Medical and Biological Engineering, Fellow of the Royal Society of Chemistry

Gu Zhongze is currently the Dean of the School of Biological Science and Medical Engineering of Southeast University, the director of the State Key Laboratory of Digital Medical Engineering, and the chairman of the Organoid-on-a-Chip Branch of the Chinese Society of Biomedical Engineering. He has been engaged in research on human organ chip for a long time, and his research results have published more than 400 papers in international core journals. Won more than 100 national invention patents, transferred 13 patents. He has won the first prize of Natural Science of the Ministry of Education, the first prize of Science and Technology Award of Jiangsu Province, and presided over the key scientific problems of Transformative technology under the National Key Research and Development Program, the 863 high-tech research and Development Program, and the key projects of the National Natural Science Foundation.

Yun Liu
President of Jiangsu Province Hospital (the First Affiliated Hospital with Nanjing Medical University); Vice President of Nanjing Medical University; Vice Dean of School of Biomedical Engineering and Informatics, Nanjing Medical University; Director of Institute of Medical Informatics and Management, Nanjing Medical University.

LIU Yun, Level-2 professor, doctoral supervisor, Level-2 Doctor-in-charge, president of Jiangsu Province Hospital (the First Affiliated Hospital with Nanjing Medical University), director of Institute of Medical Informatics and Management of Nanjing Medical University, member of the National Committee of the CPPCC, deputy director of Jiangsu Committee of Chinese Peasants And Workers Democratic Party, State Council Special Allowance Expert, chief scientist of National Key R&D Program of China, Vice Chairperson of the Standards Committee of Chinese Medical Information and Big Data Association, winner of the "National Labor Day Medal" in Jiangsu province, "National advanced individual in the fight against COVID-19", Top medical talent in Jiangsu province, outstanding key medical talent of health promotion project by science and education in Jiangsu province, and key medical talent of health strengthening project by science and education. Prof. Liu has received multiple honors in academic area, including the second prize of Jiangsu Provincial Science and Technology Award, undertaken 20 national and provincial projects, published nearly 100 SCI papers, edited and translated 4 books, and holds 6 national invention patents.

Kam W. Leong
A member of the National Academy of Engineering, the National Academy of Inventors, the National Academy of Medicine, and the Samuel Y. Sheng Professor in the Department of Biomedical Engineering at Columbia University.

Kam Leong is the Samuel Y. Sheng Professor of Biomedical Engineering at Columbia University, and holds an Interdisciplinary Faculty position in the Department of Systems Biology. He is a pioneer in developing multifunctional nanoscale technologies for delivering drugs, antigens, proteins, siRNA, and DNA to cells. Innovations in the Leong Lab include biomaterials such as electrospun nanofibers for controlled release and tissue engineering, synthesis of biocompatible and near-infrared-emitting quantum dots, nucleic acid-binding polymers, and microfluidic platforms for nanomedicine. He has also designed nonviral gene delivery mechanisms for hemophilia treatment, genetic immunization, and cellular reprogramming. His recent work has focused on directly reprogramming adult cells from one lineage to another without going through the intermediate pluripotent state. His lab is particularly interested in how such approaches, based in tissue engineering and regenerative medicine, could offer new strategies for treating neurodegenerative disorders such as Alzheimer’s and Parkinson’s diseases.
Dr. Leong is internationally recognized as a leader in the development of nanoscale therapeutics. In 2013 he was elected a Member of the USA National Academy of Engineering and a Member of the USA National Academy of Inventors.

Special Invited Guests

Academician Yeguang Chen

He is the director of the Chinese Society of Cell Biology, the president of the Asia-Pacific Society of Cell Biology (APOCB), and the editor of Cell Regeneration magazine. He mainly uses organoid model of digestive tract development and disease occurrence to explore the signal transduction mechanism of TGF-β and Wnt, as well as their roles in stem cell self-renewal and differentiation and tumor formation.

Academician Xiaosong Gu

Director of the National Key Laboratory of Advanced Medical Materials and Medical Devices, Director of the Key Laboratory of Research and Evaluation of Tissue Engineering Technology Products of the State Drug Administration. Vice Chairman of the Chinese Society of Biomedical Engineering, honorary chairman of the Chinese Society of Anatomy, and deputy editor of the international English journal Curr Stem Cell Res Ther.


Foreign guests

1

Kam W. Leong

A member of the National Academy of Engineering, the National Academy of Inventors, the National Academy of Medicine, and the Samuel Y. Sheng Professor in the Department of Biomedical Engineering at Columbia University.

TBD

2

Danilo A. Tagle

Director, Office of Special Initiatives at the National Center for Advancing Translational Sciences (NCATS) of the National Institutes of Health (NIH), USA

The NIH Microphysiological Systems Program: Tissue on Chips for Safety, Efficacy and Precision Medicine Studies

3

Thomas Hartung

Director of the Johns Hopkins Center for Alternatives to Animal Testing

The state of the MPS revolution

4

Uwe Marx

Honorary Professor for Medical Biotechnology at the Technische Universität Berlin, Germany;
CEO & CSO of TissUse GmbH, Germany

Integrating human organoids into organismoids – how to achieve human body homeostasis in vitro?

5

Kaiming Ye

Professor and Department Chair of Biomedical Engineering and director of the Center of Biomanufacturing for Regenerative Medicine at the Binghamton University (BU), State University of New York (SUNY)

TBD

6

Takao Ashikaga

Section Chief, Division of Risk Assessment, Biological Safety Research Center, National Institute of Health Sciences, Kanagawa, Japan

International standardization policy for MPS in Japan and development of in vitro respiratory toxicity test as an example of applied research.

7

Bas van Balkom

Assistant professor in the Dept of Nephrology and Hypertension, UMC Utrecht

Investigating extracellular vesicle-based therapeutic options using alternatives for animal models

8

Lorna Ewart

CSO of Emulate, USA

Performance assessment and decision making capabilities of Liver-Chip to detect drug-induced liver injury

9

Olivier Guenat

Professor, Head Organs-on-Chip Technologies, ARTORG Center for Biomedical Engineering Research, University of Bern, Switzerland

Organs-on-Chip Models of the Lung Parenchyma

10

Seiichi lshida

Professor, Division of Applied Life Science, Graduate School of Engineering, Sojo University, Kumamoto, Japan

The recent progress of MPS development and its implementation to regulatory acceptance in Japan.

11

Lena Smirnova

Assistant Professor of Environmental Health and Engineering at Bloomberg School of Public Health, Johns Hopkins University

Advanced 3D brain MPS understanding neuronal network dynamics

12

Lisa Levin

Alternatives Director for Coridea, LLC, USA

Outcomes from a Multistakeholder Engagement to Address the Challenges Associated with the Development, Regulatory Approval, and Implementation of Non-Animal Methods in Biomedical Research, Drug Development, and Safety Testing

13

Jan Lichtenberg

Co-Founder & CEO of InSphero Inc., Zurich, Switzerland

TBD

14

Marian Raschke

Head of Laboratory Advanced Cellular Models, Bayer Pharmaceuticals, Germany

Advanced Cellular Models in the Pharmaceutical Industry – Current Use Cases and Future Perspectives

15

Alastair Stewart

Chair of Pharmacology and Therapeutics at the University of Melbourne; Director of the ARC Industrial Transformation Centre for Personalised Therapeutic Technologies; CSO and Director of TianLi Biotech; President of the Asia Pacific Federation of Pharmacologist

Circadian Rhythm in MPS for CLOCK-targetting therapeutics

16

Janos Vörös

Head of Laboratory of Biosensors and Bioelectronics, Institute for Biomedical Engineering, University and ETH Zurich, Switzerland

Well-defined neural networks on a chip

17

Yong Chen

Professor of Ecole Normale Supérieure (ENS); Directeur de Recherche (1st class) of CNRS and head of the ENS team for microfluidics, France

A general organ-chip system for advanced applications

18

Xuexuan Wang

Director, WuXi AppTec, Laboratory Testing Division, DMPK

The Applications of Organ Chips in DMPK Research – A Review and Perspectives

Chinese Guests(Sort by last name)

1

Liang Chen

Professor, Director of Department of Thracic Surgery, Jiangsu Province Hospital; Chairman of the Thoracic Surgery Branch of Jiangsu Medical Doctor Association; Former Chief Member of Jiangsu Provincial Medical Association, Thoracic Branch

The precise minimally invasive treatment of early-stage lung cancer

2

Pu Chen

Professor, Chair of Department of Biological Science & Medical Engineering, Wuhan University Taikang Medical School

Reproducible Production of Bioengineered Brain-Organoid-on-a-Chip in a Microplate

3

Zaozao Chen

Associate Professor, School of Biological Science and Medical Engineering, Southeast University; CTO of Jiangsu Avatarget Biotechnology Co.

Potential of Microphysiological System in drug development

4

Zhimin Fan

Chief TCM physician, Professor, Prestigious Doctor of Chinese Medicine in Jiangsu Province, Vice Chairman of Anorectal Branch of China Association of Chinese Medicine, Chairman of Anorectal Branch of Jiangsu Association of Chinese Medicine

Construction and Clinical Translation of Colorectal Cnacer Organoid Research System

5

Qi Gu

Director of Organ Engineering Laboratory at the Institute of Organ Manufacturing, Chinese Academy of Science

How close is organ fabrication to achieving the natural complexity?

6

Zhongze Gu

Director of Organ Engineering Laboratory at the Institute of Organ Manufacturing, Chinese Academy of Science

The Integration of Organs-on-Chip and Artificial Intelligence

7

Di Huang

Professor, Deputy Dean at School of Biological Science & Medical Engineering, Taiyuan University of Technology

Lung-on-a-Chip Model and Printing Small-Size Blood Vessels

8

Kuirong Jiang

Chief Surgeon, Professor of General Surgery, Vice Director of Department of General Surgery, Director of Pancreas Center, Vice President of the First Affiliated Hospital of Nanjing Medical University

Organoid Models and Microfluidic Platforms in Pancreatic Cancer

9

Xingyu Jiang

Chair Professor of Department of Biomedical Engineering, Southern University of Science and Technology; Fellow of the Royal Society of Chemistry (UK) and American Institute of Medical and Biological Engineering

Electronic blood vessels for regeneration

10

Mingxing Lei

Professor, Chair of Department of Biological Engineering, Chongqing University

Skin Organoids and Hair Regeneration

11

Ling Leng

Professor, Chinese Academy of Medical Sciences & Peking Union Medical College; Director of Stem Cell Quality Control Laboratory at Peking Union Medical College

Construction and Application of Complex Skin Organoid

12

Chenzhong Li

Professor of Biomedical Engineering, Biochemistry, The Chinese University of Hong Kong, Shenzhen; Fellow of National Academy of Inventors (NAI); Fellow of the American Institute for Medical and Biological Engineering (AIMBE), Co-Editor-in-Chief of the journal Biosensors and Bioelectronics (Elsevier)

Application of SPR measurement system with integrated cell and tissue chip in cancer and myocardial drug screening

13

Gang Li

Associate Professor, Chief Physician of Nanfang Hospital

Nasopharyngeal Carcinoma Organoid and Nasal-Mucosa-on-a-Chip

14

Xiangning Li

Professor of Hainan University School of Biomedical Engineering

Mesoscopic Dissection of Neural Circuit in Ageing and Degeneration Disease

15

Xiaohong Li

Chief Scientist of National Key R&D Program, Tianjin University

Design and Development of Brain Intelligence Complex for Tissue Engineering

16

Geyu Liang

Deputy Dean, Professor, Doctoral Supervisor, School of Public Health, Southeast University

Nanoplastics Pulmonary Toxity Study Based on Lung-on-a-Chip

17

Hao Liang

Director of Guangxi Medical University Life Science Institute

Exploring the Application of Organoids in Research on Emerging and Highly Pathogenic Infectious Diseases: Unveiling the Power of Disease Models

18

Yan Liu

Vice Director / Professor from the Institute of Stem Cell and Neural Regenerative Medicine, School of Pharmacy, Nanjing Medical University

Human Brain Organoids and Neurological Disease Research

19

Zuhong Lu

Professor of Biomedical Engineering, Southeast University

 

20

Ling Lv

Vice President of Xuzhou Medical University, Professor, Chief Physician

Application and Translational Research of Organoid and Organ-on-a-Chip for Hepatobiliary Disease

21

Jianhua Rao

Deputy Chief Physician / Associsate Professor, The First Affliliated Hospital, Nanjing Medical University

Construction and Precision Applications of Liver Cancer's Organoids

22

Tao Wang

Administrative Deputy Director of Cardiothoracic Surgery, Nanjing Drum Tower Hospital

TBD

23

Zhimin Wang

Professor, Shanghai Institute for Biomedical and Pharmaceutical Technologies, PI of Interdisciplinary Research Group (IRG), Former Professor and Executive Deputy Director of Shanghai Heshceler (Stem Cell) Institute, Shanghai Industrial Technology Institute

From PDC-PDO-PDX-PDA to Organoids-on-a-chip -- A Discussion on Scientific Research and Clinical Application

24

Chunyang Xiong

Professor at Department of Mechanics, Peking University

Cellular Mechanical Stimulating and Phenotyping on Chip

25

Leping Yan

Deputy Director of the Medical Ethics Research Office,SunYat-Sen University School of Medicine; Co-Editor of the journal In Vitro Models (Springer)

Construction of High-Fidelity Digestive System Tumor Microenvironment Models

26

Fei Yang

Dean of School of Public Health, University of South China

Modeling MC-LR-induced neurotoxicity using human induced pluripotent stem cell-derived cerebral organoids

27

Rong Yin

Vice President of Jiangsu Cancer Hospital, Research, Professor, Deputy Director of Jiangsu Key Laboratory of Molecular and Translational Cancer Research

Construction and Clinical Transformation of Lung Cancer Organoids

28

Juan Zhang

Chair of School of Public Health, Southeast University

TBD

29

Quanshun Zhang

Senior Scientist and Program Director for Education and Outreach, Institute for In Vitro Sciences

Advanced in Vitro Test Systems in Respiratory Toxicology

30

Ying Zhang

Associate Researcher, School of Biological Science and Biomedical Engineering, Southeast University

Biomimetic Hydrogel Materials in Organoid Culture

31

Bing Zhao

Professor, School of Life Sciences, Fudan University

Application of organoid technology in disease modeling and translational medicine

32

Chen Zhao

Professor of Nanjing Medical University, Deputy Chairman of Committee for Drug Clinical Evaluation Research of the Jiangsu Pharmaceutical Association

Integration and Application of Quantitative Systems Pharmacology Modeling and MPS in Modern Drug Development

33

Xiaobing Zhou

Research Fellow, Head of the Toxicology Department of National Center for Evaluation of Drugs of NIFDC

Regulatory Considerations for the Application of Organ-on-Chip in Drug Development

34

Dan Zhu

Distinguished Professor with the Huazhong University of Science and Technology, Wuhan, China; Vice Director with Wuhan National Optoelectronics Laboratory, Wuhan China

Tissue Optical Clearing Imaging

35

Jiangbo Zhu

Professor, Department of Health Toxicology, Naval Medical University

Application of Organ-on-a-Chip Technology in Drug Toxicology